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HCB-813 General and Molecular Immunology
Campus ASAB
Programs PG
Session Fall Semester 2016
Course Title General and Molecular Immunology
Course Code HCB-813
Credit Hours 3-0
Pre-Requisutes
Course Objectives This course will cover basic concepts of immunology and the mechanism by which T and B lymphocytes acquire high level of specificity. Surface molecules will be described in detail, followed by accessory and natural killer cells and human lymphocyte antigen. Autoimmunity and tolerance will also be discussed.
Detail Content
  • The immune system
  • Origins of the immune system
  • Antibody structure and function and antibody diversity
  • Helper T cells and their activation
  • Organs of the lymphatic system
  • T lymphocyte development and differentiation
  • B cell lymphocyte Development and Differentiation
  • Cell-cell interaction (T cells and Antigen presentation cells)
  • Non specific Defense Cells (Natural Killer cells)
  • Monocytes and Dendritic cells
  • HLA system (genomic organization, molecule structure, class I/II alleles and antigen
  • presentation).
  • The complement system
  • Innate immunity
  • Leukocyte migration
  • Pathological Immune mechanisms and tolerance
Text/Ref Books
  • Introduction to Immunolgyby J.W. Kinhall, 1983, Macmillan Pub Co.
  • Immunology by Richard A.Goldsby, Thomas j.Kindt, Barbara A. Osborne, Janis Kuby, 2005. W.H Freeman and Co.
  • Cellular and Molecular Immunology by Abbas, 2005. Elsevier Pub Co.
  • Color Atlas of Immunology by G.R. Burmester, A. Pezzutto, 2006. Thieme Stuttgart, New York.
Time Schedule Semester 2014
Faculty/Resource Person Dr. SheebaMurad Mall
PhD (Medical University of Vienna, Austria
Discipline: Immunology