National University of Sciences and Technology
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IBT-923 Mammalian Cell Processing
Campus ASAB
Programs PG
Session Fall Semester 2016
Course Title Mammalian Cell Processing
Course Code IBT-923
Credit Hours 3-0
Course Objectives The course will provide basis for mammalian cell processing from cell culture engineering to media development to metabolic engineering
Detail Content
  • Overview of mammalian cell culture
  • Ultra scale down methodologies
  • Cell line engineering
  • Case Study: From development to production
  • Modelling mammalian cell cultures
  • The application of process analytical technologies
  • Metabolic engineering and proteomics
  • Scale-up of protein-free production processes
  • Single use technologies for upstream processing
  • Cell line selection
  • Cell therapy
  • Medium development and optimization
  • Stem cell biology and the current status of stem cell therapy
  • Engineered tissues as replacement body parts and as replacements for animal testing
  • Key issues and tools used in industrial cell culture operations, including economies of scale, operations management, control charts, and process flow diagrams
Text/Ref Books
  1. Mammalian cell biotechnology in protein production by Hauser and Wagner. Berlin: Newyork: de Gruyter.
  2. Gene Transfer and Expression in Mammalian Cells by Savvas C. Makrides. Gulf Professional Publishing
  3. Protein therapeutics production: large-scale mammalian cell culture by Alfred Doig, Tracy Beaudoin. D&MD Publications
Time Schedule Fall Semester 2014
Faculty/Resource Person Dr. ShazinaKanwal
PhD (Paris VI)

Discipline: Endocrinology, Metabolism and Cancerology