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IBT-923 Mammalian Cell Processing
Campus
ASAB
Programs
PG
Session
Fall Semester 2016
Course Title
Mammalian Cell Processing
Course Code
IBT-923
Credit Hours
3-0
Pre-Requisutes
Course Objectives
The course will provide basis for mammalian cell processing from cell culture engineering to media development to metabolic engineering
Detail Content
Overview of mammalian cell culture
Ultra scale down methodologies
Cell line engineering
Case Study: From development to production
Modelling mammalian cell cultures
The application of process analytical technologies
Metabolic engineering and proteomics
Scale-up of protein-free production processes
Single use technologies for upstream processing
Cell line selection
Cell therapy
Medium development and optimization
Stem cell biology and the current status of stem cell therapy
Engineered tissues as replacement body parts and as replacements for animal testing
Key issues and tools used in industrial cell culture operations, including economies of scale, operations management, control charts, and process flow diagrams
Text/Ref Books
Mammalian cell biotechnology in protein production by Hauser and Wagner. Berlin: Newyork: de Gruyter.
Gene Transfer and Expression in Mammalian Cells by Savvas C. Makrides. Gulf Professional Publishing
Protein therapeutics production: large-scale mammalian cell culture by Alfred Doig, Tracy Beaudoin. D&MD Publications
Time Schedule
Fall Semester 2014
Faculty/Resource Person
Dr. ShazinaKanwal
PhD (Paris VI)
Discipline: Endocrinology, Metabolism and Cancerology