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ABS-932 Genomics, Proteomics and Bioinformatics
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Campus
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ASAB
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Programs
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PG
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Session
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Fall Semester 2016
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Course Title
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Genomics, Proteomics and Bioinformatics
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Course Code
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ABS-932
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Credit Hours
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3
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Pre-Requisutes
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None
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Course Objectives
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- This course educates and develops skills in students who desire to work to solve problems related to genomics and proteomics by using bioinformatics tools.
- Offers students an opportunity to practice accessing and using online databases to engage in real-time discoveries using the same approach current scientist’s use in their own research.
- Focuses on the process of doing genomic analysis and thinking from a genomics perspective.
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Detail Content
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- Introduction to genomics
- Gene Expression Gene-chips/Microarrays, Technical methodology and analyses of microarray data; brief overview of proteomics
- How genomes are annotated
- Use of Genomics in biomedicine Mutations, alleles and single nucleotide polymorphisms (SNPs), Genetic testing
- Overview of genomics projects
- Genome analysis Bioinformatics, Data-mining, Prediction of open reading frames, Characteristic sequence features, and regulatory sequences; Familiarity with whole genome browsers
- Proteomics, Trancommentomics, Metabolomics, Protein structures and function
- Molecular phylogeny and evolution, Gene Finding and Sequence Annotation
- Bioinformatics for Cancer Genomics, Homology modeling
- Predicting Protein Structure and Function from Sequence
- Data mining, Applications of bioinformatics
- Ethical, social and philosophical considerations
- The Ultimate Genomic Phenotype- Death, Aging and the hidden costs for a prolonged life, Patent Law and Genomics, Genetically Modified Organisms
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Text/Ref Books
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- Beginning Perl for Bioinformatics by James Tisdall. O'Reilly. 2001.
- Learning Perl - Making Easy Things Easy and Hard Things Possible by Randal L. Schwartz, Tom Phoenix, brian d foy. O'Reilly. 2008.
- The processes of life an introduction to molecular biology by Lawrence Hunter. MIT Press, 2009.
- Essential Cell Biology by Alberts et al. Garland Science. 3rd Edition.
- Molecular biology of the cell by Bruce Alberts et al. Garland Science. 5th Edition.
- Bioinformatics edited by Paul H. Dear. Method Express, 2007.
- Discovering Genomics, Proteomics, & Bioinformatics by A. Malcolm Campbell and Laurie J. Heyer. Pearson. 2nd Edition, 2007.
- Genomics, Proteomics, & Bioinformatics by Campbell and Heyer
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Time Schedule
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Faculty/Resource Person
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Assistant Professor – Dr. Sadia Zahid (PhD)
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